Enhancing the public health impact of latent tuberculosis infection diagnosis and treatment: A pragmatic cluster randomised trial


STUDY SITES: Quang Nam and Da Nang province

COMPLETED: March 2019

PROJECT IMPLEMENTERS: National Lung Hospital / National TB Program

PARTICIPATING COUNTRIES: Canada, Benin, Ghana, Brazil, Indonesia, Vietnam

FUNDED BY: Canadian Institute of Health Research (CIHR)

CORE STAKEHOLDERS: Da Nang Lung Hospital and Quang Nam Pham Ngoc Thach Hospital

PRIMARY OBJECTIVE: To estimate the increase in number of close contacts (of pulmonary tuberculosis patients) who are identified, investigated, initiated, and completed latent tuberculosis infection (LTBI) therapy. The intervention is a standardised public health evaluation (Cascade analysis), with use of operational modeling analysis to select effective interventions from a "public health toolkit".

This study was registered as a clinical trial under number: NCT02810678

OUTCOMES: Analysis of this study is currently underway.